21 Nifedipine side effects and Doses

By | June 11, 2020
Nifedipine side effects

Nifedipine side effects and doses – Nifedipine is a drug with a function to prevent certain types of chest pain (angina), and hypertension. This remedy enables you to more exercise and reduce the frequency of angina attacks. Nifedipine belongs in a class of drugs known as calcium channel blockers.

These drugs work by relaxing the blood vessels so that blood can flow more easily.

This medication should be used regularly to be effective. This drug should not be used to treat attacks of chest pain at the time. Use of other drugs (such as sublingual nitroglycerin) to relieve attacks of chest pain as recommended by your doctor. Consult a doctor and pharmacist for more information.

Nifedipine works by inhibiting the amount of calcium in the cells of the heart and blood vessels. This condition will dilate the blood vessels, thereby increasing the supply of blood and oxygen to the cells of muscles, including the heart muscle, as well as lighten the workload of the heart.


  • Patients with impaired processing of sugar in the body, such as lactose intolerance, not recommended taking nifedipine.
  • Avoid the use of nifedipine in heart failure patients.
  • Use with caution in patients with cardiomyopathy.
  • Careful use of elderly patients, because it can cause hypotension.
  • Notify doctor that drugs routinely consumed, including supplements and herbs.

Doses Of Nifedipine.

The dosage of these drugs is influenced by various factors, i.e. what diseases arising, whether there is a history of allergy to this medicine, a person’s body response against this drug, as well as other diseases that can react if consumption of the Nifedipine drug.

Angina Pectoris Prophylaxis.

Oral tablets-immediate-release capsules.

  • Initial dose: 10 mg per oral 3 times a day.
  • Treatment dose: 10 to 30 mg per oral 3 to 4 times a day.
  • Maximum dose: 180 mg/day.

Oral-tablets extended-release tablets.

  • Initial dose: 30 to 60 mg per orally once daily.
  • Maintenance dose: 30 to 90 mg per orally once daily.

Raynaud’s Syndrome.

Oral tablets.

  • Older people dose: 5-20 mg, 3 times per day.


Oral tablets-immediate-release capsules.

  • The initial dose of 5 mg, 3 times per day.
  • Advanced dose: 10-20 mg, 3 times per day.

Oral-tablets extended-release tablets:

  • 10-40 mg, 2 times a day or 30-90 mg, once a day.

Angina Pectoris

Oral tablets.

  • Initial dose for older people: 5 mg, 3 times per day.
  • Advanced dose: 10-20 mg, 3 times per day.

Nifedipine side effects.

Nifedipine side effects for liver function

All drugs must have side effects, but not all people will experience these side effects.

Side effects that may occur during the use of Nifedipine, among others:

  • Effect of CV (cardiac function, depression, hypotension, worsening heart failure, bradycardia); Palpitations (irregular heart rate); Tachycardia (heart rate when resting above the normal limit); myocardial infarction; angina.
  • The GI effects: Gastrointestinal disorders include nausea, vomiting, constipation, cholestasis, obstruction
  • Extremities: peripheral edema; Myalgia (muscle pain).
  • Edema (swelling due to a buildup of fluids in certain parts of the body)
  • CNS effects / Neurology: headache, dizziness; Vertigo (spinning headaches); Migraine (side headache); Tremor / seizures.
  • HR set the calcium antagonist (such as Diltiazem, Verapamil and Gallopamil); decomposition of AV, AV block, bradycardia & sinus stem disorders.
  • Dihydropyridine agents short interaction should be avoided because it has the potential to raise the risk of worsening the heart condition.
  • Hypotension (low blood pressure)
  • Languid
  • Eyes: pain, disorders of refraction, visual impairment
  • Syncope (fainting)
  • Psychological: mood disorders
  • Disorders of liver function, including cholestasis (inhibition of bile flow)
  • Pruritus (Itching at all parts of the body).
  • Hyperplasia of the gingiva (gum swelling).
  • Gynecomastia (increased bre**ast size in men).
  • Genitourinary: impotence, urination frequency.
  • Systemic: fever, flushing
  • Allergy: itching, rash, stevens johnson syndrome, erythema multiforme, exfoliative dermatitis. Rash, including Erythema (redness of the skin caused by dilation of vessels).
  • Respiratoric: dyspnea, coughing, wheezing, nasal congestion, sore throat
  • Other: gingival hyperplasia

If the Nifedipine side effects persist even worse, immediately discontinue its use and consult a doctor.

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