15 Cholestyramine Side Effects, Warning, and Rules of Use

By | December 25, 2019
Cholestyramine Side Effects

Cholestyramine Side Effects, Warning, and Rules of Use – There are a variety of ways to lower cholesterol. One of them is with medical treatment. It does not hurt you who have a history of cholesterol to know the usefulness and how to use the medication that the Doctor prescribe for you. One of the most common cholesterol-lowering drugs is Cholestyramine.

Cholestyramine is used to lower high cholesterol levels in the blood so it can help reduce the risk of stroke and heart attack. This drug can also be used in patients to reduce excessive bile acids, which may result in itching.

Read also: 18 Sources Of Cholesterol: High Bad and Good Cholesterol

Cholestyramine is a bile acid binding drug to be disposed of from the body. By removing bile acids, the liver will use a lot of cholesterol to make new bile acids, so the drug is widely used to lower high cholesterol in the blood.

In addition, Cholestyramine is also used to cope with itching on the blockage of the bile duct, either due to liver disease or bile duct itself. However, this still requires further research, since itching on the blockage of the bile duct is not only influenced by the accumulation of bile acids.

The rules of drug use.

Cholestyramine can be consumed with or without food. Do not consume cholestyramine in dry powder, but mix cholestyramine powder with 150 mL of water, fruit juice, soup, or milk, then stir until evenly before drinking it. The use of this drug is adjusted to the medical condition and response to treatment. Before taking this medication, consult a physician first. Avoid long-lasting mixture in the mouth, as it can damage the teeth.

Because Cholestyramine can lower the absorption of other drugs, take another drug 1 hour earlier, or 4 to 6 hours after taking cholestyramine. To obtain maximum medicinal benefits, drink cholestyramine regularly. It is advisable to still take this drug even, in a healthy state according to the doctor’s advice.


  • Please be careful if you are suffering or have a history of kidney, constipation, or hemorrhoidal disease.
  • Cholestyramine can affect the absorption of certain nutrients, such as folic acid and fat-soluble vitamins such as vitamin A, D, E, K.
  • Cholestyramine is available in powder form, never swallowing directly the powder without being dissolved in water because of the risk of choking.
  • Prolonged use may result in the risk of bleeding.
  • In case of an allergic reaction or overdose after taking cholestyramine, consult a doctor immediately.
  • Cholestyramine does not address cholesterol problems, but helps control it. It is important to do exercise and diet with balanced nutrition.

Read also: The natural way to lower cholesterol

Cholestyramine Side Effects

Seek help when you feel some signs of allergic reactions such as rash, shortness of breath, or swelling of the face, tongue, lips or throat.

Cholestyramine Side Effects - Constipation

Commonly found Cholestyramine side effects include:

  • Constipation
  • Abdominal pain, nausea or vomiting
  • Ulcer
  • Flatulence
  • Inflammation of the tongue
  • Rash on skin
  • Stools are clogged.
  • Hemorrhoids.
  • Itching of the tongue, skin and anus.
  • Vitamin A and D deficiency (rarely occurring).

Contact your doctor immediately when you find:

  • Bloody urine
  • Great abdominal pain
  • Heavy constipation
  • Bloody or Black defecate.
  • Easy bruising or unusual bleeding

Read also: 24 Side Effects of Pravastatin

Cholestyramine overdose effect

Use with a high dose of 150% of the recommended dose of the doctor is reportedly able to cause an overdose effect. If symptoms of severe abdominal pain, bloating and difficult to dispose of the flirt, constipation and vomiting can be a sign of overdose, immediately take the sufferer to the hospital in order to get help immediately.

Can Cholestyramine drug be consumed by pregnant and nursing women?

Cholestyramine is in category C for pregnant women. This means studies in animal experiments show the presence of side effects on the fetus (teratogenic or embryocidal or other side effects) and there have not been any controlled studies in women, or studies of women and animal experiments cannot be carried out. Therefore, its use should be very necessary if it is needed and the usefulness is quite large compared to the side effects.

Cholestyramine is known to be extracted in breast milk, therefore, its use should be consulted with the doctor first.

Thank you very much for reading Cholestyramine Side Effects, Warning, and Rules of Use, hopefully useful.

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