Parkinson’s Disease: 7 Facts, Stages, Causes, Risk Factors, and Treatment

By | June 30, 2020
Parkinson's Disease

Parkinson’s disease is a nerve disease that deteriorates gradually and affects the part of the brain that serves to coordinate body movements. As a result, people have difficulty regulating their body movements, including speaking, walking, and writing.

Parkinson’s Disease Facts

The disease is progressive and does not have curative care. The disease was discovered by James Parkinson in 1817 and experienced about 10-25 people from every 10,000 people. The facts on Parkinson’s disease are:

  • Parkinson’s disease occurs due to brain nerve cells.
  • Unknown cause medically.
  • Usually occurs in the age of 60.
  • Experiencing Tremor.
  • Muscles Stiff and Pain.
  • Divided into 5 Stadium.
  • Healing with 3 Types of Therapy.

Parkinsons stages

As previously said, the disease deteriorates gradually as time goes by, and is divided into 5 stages (stages) as described below:

Stage 1.

At stage 1, symptoms of Parkinson’s disease are mild and do not interfere with sufferers.

Stage 2.

The period of development of Parkinson’s disease from Stage 1 to Stage 2 is different in each sufferer, it can take place in a matter of months or years. At this stage, symptoms begin to appear.

Stage 3.

Parkinson’s disease Stage 3 is characterized by increasingly apparent symptoms. Gestures begin to slow down, and start disrupting sufferers ‘ activities.

Stage 4.

At this stage, the sufferer begins to trouble standing or walking. The mobility of sufferers will be slowed down, requiring the help of others to support their activities.

Stage 5.

Parkinson’s disease Stage 5 can make the sufferer difficult or can not even stand at all.

Patients may also experience delusions and hallucinations.

Parkinson’s Disease Causes

Parkinson’s disease is associated with damage or death of nerve cells in the part of the brain called Susbstantia nigra. These nerve cells function in producing dopamine, a chemical compound that sends messages from the brain to the nervous system, and helps control gestures.

In people with Parkinson’s disease, nerve cells in the substantia nigra are damaged or die, so the amount of dopamine in the brain decreases. As a result, the motion of the body becomes slow and abnormal.

The condition of the nerve cells that dies and cause reduced dopamine, is a slow-lasting process. New Parkinson’s disease symptoms appear when the number of nerve cells in the dead Susbstantia nigra reaches 80 percent.

It is not yet known what causes nerve cells to malfunction or die. However, the condition is thought to be related to the following factors:

  • Hereditary factors. About 15 percent of Parkinson’s disease people has family members with the same history of illness. In such cases, Parkinson’s disease can be caused by mutations in genes.
  • Environmental factors. Exposure to toxins such as pesticides, herbicides, air pollution due to industrial activity or motorized vehicle smoke, may increase the risk of developing Parkinson’s disease.

In addition to the above two factors, Parkinson’s disease is also associated with abnormal protein clot. A protein clot called Lewy Bodies is formed in brain nerve cells that produce dopamine.

Although not yet known for a sure cause, research suggests that Parkinson’s disease is more susceptible to attack men than women, and individuals aged 60 years and above.

Risk factors for Parkinson’s disease


Young older persons rarely experience Parkinson’s disease. The disease usually starts attacking middle age to elderly, with increased risk as you age. Ages 60 or above will be more at risk of developing this disease.


Having a close relative to Parkinson’s disease will increase the risk of this disease. However, this risk is small, unless it has many relatives in the family with a history of Parkinson’s disease.


Men more often suffer from Parkinson’s disease than women.

Exposure to toxins.

Exposure to herbicides and pesticides allegedly increases the risk of Parkinson’s disease.

Read also:
Risk factor for dementia

Parkinson’s Disease Treatment

Until now, no therapy can cure Parkinson’s disease. However, there are several ways to control it:

First therapy

At this stage is done with treatment. The people are given a drug that can increase dopamine levels in the brain.

Second therapy.

Parkinson’s can do thalamotomy therapy. This therapy is surgical by burning brain tissue damaged by Parkinson’s.

Third therapy

At this stage, the therapist will use deep brain stimulation. This therapy uses the chip inside the brain to stimulate brain dopamine levels.

Read also:
How To Prevent Parkinson’s Disease

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